The liver plays a vital role in the body, carrying out essential functions such as detoxifying the blood, producing bile, and storing important nutrients.

But when the liver isn’t working as it should, it can trigger pain or discomfort in different areas. These warning signs shouldn’t be ignored. Below are the key regions where liver issues may show up as physical symptoms.

1. Discomfort in the Upper Right Abdomen

Pain located in the upper right section of the abdomen is one of the clearest indicators of liver trouble. Since the liver sits just below the diaphragm on the right side, any inflammation, damage, or swelling can lead to noticeable discomfort here.

This pain might feel like a dull ache or even a sharp, stabbing sensation. Conditions like hepatitis, cirrhosis, or a fatty liver are often responsible for these symptoms.

2. Pain in the Right Shoulder or Upper Back

Because the liver is so close to the diaphragm, liver issues can cause pain that radiates to the upper right back or even the right shoulder.

This type of discomfort is known as “referred pain” — the brain perceives pain from the liver as coming from other areas. People with chronic liver disease or liver masses frequently report this symptom.

3. Widespread Abdominal Pain

Sometimes, liver problems don’t stay confined to one spot. Instead, people may feel a general ache across the entire abdominal area.